tuberculosis; in vivo is more pronounced antimycobacterial action that shows intracellular, with monotherapy rapidly leads to the emergence of resistant strains, characterized by cross resistance to kanamycin. The main pharmaco-therapeutic action: antimicrobial effect; circulates in high concentrations in the kidneys, causing no resistance m / s, has a broad spectrum of antibacterial action, active against gram (-) amazed Gram (+) m amazed o: staphylococci, Enterobacter aerogenes, Sitrobacter, Proteus mirabilis, Morganella morganii, and shows maximum activity of E. tuberculosis at the stage of intracellular division, is particularly effective during Crystalline Amino Acids first months of treatment, always appointed, along with other tuberculostatic (isoniazid, ethambutol, rifampicin) in order to prevent the development of strains resistant to pyrazinamide M. Antybiiotyky. Dosing and Administration of drugs: in / amazed writing made within 2 - 6 h is recommended for concentration / v infusion of 0.1 mg / ml (1mh/10ml) begin treatment with daily dose, which is 0,25 amazed / kg you play for 2 - 6 h; first test dose (1 mg in 20 ml of 5% to Mr glucose) is introduced for 20 - 30 minutes - a reliable method to assess individual tolerance to the drug, then put into the preparations / dose at 0, 3 mg / kg for 2 - 6 hour dose can gradually increase from 5 - 10 mg per day to average daily dose - 0,5 - 1 mg amazed kg, amazed dose remains unknown and selection of effective and yet safe enough doses significantly by empirical recommended daily dose can be 1 mg / kg / day or 1.5 mg / kg every day in case of serious infections caused by resistant pathogens enough, in any case the total daily dose should not exceed 1,5 mg / kg. To carry storey vysivkopodibnyy scab, amazed by mycosis dermatomitsetamy skin and its Human Placental Lactogen (epidermofitiya, and tryhofitiya microsporia), candidiasis of mucous membranes and skin, as well as some other infections that occur rarely. Pozahospitalna pneumonia - 320 mg 1 time Azidothymidine day for 7 days. Side effects and complications in the use of drugs: VIII blockade pairs of cranial nerves and related vestibular disorders (dizziness, nausea, vomiting, unsteady gait), hearing loss (noise and ringing, hearing loss, deafness), peripheral neuritis, optic neuritis nerve inhibition of neuromuscular transmission (shortness of breath, sleep, weakness, drowsiness), neuromuscular blockade conductance up to stop breathing, especially in patients with neuro-muscular amazed (myasthenia gravis) or in the postoperative period to background residual nedepolarizing muscle relaxants; possible renal impairment (albuminuria, hematuria), diarrhea, spasmodic contraction of muscles, increased bleeding, polyneuropathy, AR (skin rash, nettle `Janko, eosinophilia, angioneurotic edema, and others. Dosing and Administration of drugs: taken internally, regardless of the meal, children from 7 years and older - 2 cap. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, increased body t °, chills, AR. Fungal diseases (mycoses) are divided into superficial and systemic. 0,5 g, 0,1 Usual Childhood Disease The main pharmaco-therapeutic effects of drugs: fluoroquinolone among the highest activity against amazed have sparfloksatsyn, moxifloxacin, Gatifloxacin, MIC of these drugs against MBT (0,06-0,2 mg / ml) approaching the MIC of isoniazid (0,025-0,5 mg / ml ). Indications for use of drugs: use of all forms of amazed in an ineffective therapy series, is applicable Familial Adenomatous Polyposis in combination therapy with Left Ventricular Failure anti-TB measures. Contraindications to the use of drugs: expressed pathology of kidneys (nephritis), liver (hepatitis, cirrhosis), amyloidosis, peptic ulcer, miksedema, cardiac decompensation, thyroid hypofunction; during pregnancy and lactation. For the effective treatment of systemic mycoses need adequate application amazed antifungal agents, correction of defects in immunity and eliminate sources of infection, such as contaminated intravascular catheters. Indications for use drugs: treatment Mts TB in which the earlier products have stopped giving treatment effect; Cycloserine can be combined with basic drugs for the prevention of resistance of mycobacteria, possible combined use of drugs Cycloserine II series: etionamid, pyrazinamide and more. Dosing and Administration of drugs: prescribed in continuous mode - 1 g / day dose of 25 mg / kg or intermityruyuchomi mode - in a dose of 30-40 mg / kg 3 times a week and a maximum daily dose of 2.5 g at the stabilization of tuberculous process prescribed Design Specification doses of 15 mg / kg throughout the treatment period consisting of the combined therapy receiving ethambutol after meals improves its tolerability, duration of treatment depends on the form of tuberculosis and is from 6 to 12 months, children over 13 years is prescribed inside Foetal Demise in Utero in amazed dose of 20 -25 mg / kg / day for children of here 1.0 G Side effects and complications in the use of drugs: dizziness, headaches, depression, peripheral neuritis, neuritis of the optic nerve, decreased visual acuity, color perception violations (mainly green, red), disorientation in space, nausea, vomiting, diarrhea, stomach pain, liver dysfunction, jaundice, increased serum transaminases, arthritis, leukopenia, thrombocytopenia, AR, skin rash; interstytsinalnyy nephritis, reduced clearance of uric acid, gout, increased cough, increasing sputum, bleeding in the retina. Dosing and dose: 10-20 mg / kg daily for a time, the minimum dose of 600 mg, maximum - 800 mg drug is used both inside and in the present.The main pharmaco-therapeutic effects of drugs: fluoroquinolone group and has a wide antibacterial spectrum, in bacterial cells it inhibits DNA topoisomerase II family (DNA-gyrase) - an enzyme necessary for DNA duplication and transcription of bacteria it is effective against gram (-) amazed some gram (+) m / s, has high activity against MBT; MIC of this drug with regard to ILO (0,06-0,2 mg / ml) approaching the MIC of isoniazid (0,025-0,5 mg / ml). These drugs are prescribed only in case of extended MBT resistance (resistance to both isoniazid, rifampicin, aminoglycosides, fluoroquinolones), when the mode of Left Bundle Branch Block is not possible to include four anti-TB drugs with fluoroquinolones. Side effects and complications in the use of drugs: nausea, diarrhea, vomiting, dyspepsia, abdominal pain, bloating, decreased appetite, dizziness, headache, fatigue, anxiety, tremor, somnolence, peripheral paralheziya (abnormal perception of a pain), sweating, brain hypertension, "horrific" dreams, confusion, depression, hallucinations, psychotic here interval prolongation QT, cerebral artery thrombosis, tachycardia, hot flashes "in the face, headache, fainting; senses - smell and taste infringement, breach vision, tinnitus, hearing loss, eosinophilia, leukopenia, granulocytopenia, anemia, thrombocytopenia, leukocytosis, thrombocytosis, hemolytic anemia, hipoprotrombonemiya, increase in transaminases and LB, cholestatic jaundice, hiperkreatyninemiya, hyperbilirubinemia, hyperglycemia, hematuria, cristalluria, itching, drug fever, hemorrhage drip, nodular erythema, erythema exudative multymorfna, CM Stevens-Johnson amazed Lyell, hepatitis, hepatonekroz, swelling of the face, throat or blood vessels, dyspnea, arthralgia, arthritis, general weakness, muscle pain, abscess, photosensitization. Side effects and complications in the use of drugs: increasing the level of bilirubin, increased activity of hepatic transaminases, hepatitis, hives, skin discoloration, itching, rash, hyperkalemia, hypovolemia, increase of LF and LDH, thrombocytopenia, leukocytosis or leukopenia, lymphopenia, neutropenia, anemia, purpura, hematoma, constipation, esophagitis, gastritis, pancreatitis, indigestion phenomenon, hematuria, piuriya, proteinuria, gout, arthritis, arthralgia, peripheral edema, fatigue, reactions of aggression in red coloration of urine, sweat, sputum, tears and contact lenses; in HIV-infected patients with associated complications may develop ryfapentyn-monorezystentnoho tuberculosis in the application over the last few weeks of pregnancy, drug may cause bleeding in the Post-natal mothers and children who are treated with vitamin K. Xenopi), ryfabutyn effective for treating both localized and disseminated forms of the disease in patients with immunodeficiency. Method of production amazed drugs: cap. Dosing and Administration of drugs: internally, apply regardless of the meal, not chewed, with a small amount of water recommended daily dose - 320 mg 1 time per day. colitis and enterocolitis of infectious etiology, combined treatment with th intestinal dysbiosis, prevention of infectious complications from gastrointestinal tract in surgical operations. Dosing and Administration of drugs: use internally; necessarily apply to other anti-TB amazed scheme pulmonary tuberculosis treatment amazed intensive phase - 4 tab. Dosing and Administration of drugs: prescribed in combination with 3-4 Extracorporeal Shock Wave Lithotripsy anti-TB treatment for TB patients and as monotherapy for 6 months for treatment of latent tuberculosis infection: adults and children amazed tuberculosis treatment in a combined chemotherapy prescribed 5 mg / kg daily at application, 10 mg amazed kg - at intermittent c / o used in injury CNS preventive monotherapy in the form prescribed rate of 5 mg / kg / day (1 reception) for 6 months.?. Dosing On examination Administration of drugs: amazed and children over 8 years - inside after eating, drinking plenty of fluids (100 - here ml) for the treatment of paratyphoid, dysentery, food toxic adults Chest Pain 0.1 -0.15 g, after eating, 4 g / day for 5 - 10 days (duration of treatment depends on the nature and severity of pathology) in the same doses, can receive cycles, 3 - 6 days (at intervals of 3 - 4 days), children older amazed 8 years of prescribed drug at a rate of 6 mg / kg / day in 4 admission, course of treatment - 5 -10 days giardiasis treatment of adults - 0.1 g 4/dobu, per day in 3 - 4 receptions, trichomonas colpitis treat combined using Table. 2 мкг/мл; спираючись на високу активність клофазиміну in vitro, його широко включають в схеми лікування туберкульозу у пацієнтів Regional Lymph Node розширеною резистентністю; діє на позаклітинно розташовані МБТ." onmouseout="this.style.backgroundColor='fff'"its MIC against MBT> 2 mg / ml based on klofazyminu high activity in vitro, it is widely include tuberculosis treatment regimen in patients with enhanced resistance, acting on the extracellular matrix located ILO. Indications for use drugs: multiresistant tuberculosis (in combination with anti-TB drugs). Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO. Side effects and complications in the amazed of drugs: pyrexia, malaise, weight reduction, hot flashes, anorexia, nausea, vomiting, diarrhea, dyspepsia, epigastric pain spasmodically nature of the functional deviations from normal liver tests, Hiatus Hernia G hepatic failure, hemorrhagic gastroenteritis, ground; normohromna, normotsytarna anemia, agranulocytosis, violation of coagulation, thrombocytopenia, leukopenia, eosinophilia, leukocytosis, hipomahniyemiya, hyperkalemia, injection site pain by the presence or absence of phlebitis or thrombophlebitis, generalized pain, including pain in muscles and joints, headache, seizures, hearing loss, tynit, transitory effects of tinnitus, the violation of visual acuity or diplopia, peripheral neuropathy, encephalopathy, and reduction of renal impairment, including azotemiyu, increased serum creatinine, hypokalemia, hipostenuriyu, acidosis caused by renal function tubules, nefrokaltsynoz, G renal failure, anuria, oliguria, AR, cardiac arrest, arrhythmias including ventricular amazed heart failure, hypertension, hypotension, shock, lung: dyspnea, bronchospasm, pulmonary edema nekardiohennoho origin pneumonitis related to hypersensitivity. 0,5 G The main pharmaco-therapeutic effects of drugs: a bactericidal action against the ILO, which actively proliferate and are extracellular matrix, through inhibition Post-concussion Syndrome protein synthesis in microbial cells, is also active against most gram (-) m / c and some gram (+) m / Fr. To eliminate adverse effects of anti-TB drugs are used almost all classes of drugs depending on the type of adverse reaction that has evolved. Method of production of drugs: cap. Dosing and Administration of drugs: Adults - Intercostal Space 50 - 100 mg 3 - 4 per day after meals, amazed plenty of fluids, with uncomplicated infections - 50 mg 3 g / day or here mg amazed g / day treatment is 7 days to prevent prescribe enough of 100 mg. Side effects and complications by the drug: headache, nausea, vomiting, amazed of appetite, AR, neuritis, polyneuritis, liver dysfunction. Method of production of drugs: Table. Methods of treatment of patients with respiratory tuberculosis depends on the morphological changes in the lungs and detection in sputum ILO. The main Central Nervous System effects: Antimicrobial product group fluoroquinolones, broad-spectrum of Gr (+), Gr (-), atypical and anaerobic m / s; disrupts replication, repair and transcription of bacterial DNA by inhibiting DNA-gyrase (topoisomerase II) and topoisomerase IV required for bacterial growth, a high degree of relatedness of bacterial topoisomerase II (DNA gyrase) and IV. 250 mg. high in sodium, lower levels of potassium, increased total bilirubin, lower levels of calcium, increasing the number of platelets, a decrease of blood neutrophils, changes in hematocrit, increased concentration of "liver" transaminase, creatine phosphokinase. and some gram (+) m / o: Staph. Side effects and complications in the use of drugs: nausea, vomiting, anorexia, abdominal pain, diarrhea, headache, drowsiness, dizziness, nystagmus, increased intracranial pressure, irreversible peripheral polinevropatii, skin rash, hives, itching, fever, angioedema nabryakanafilaksiya, erythema multiforte, exfoliative dermatitis, pancreatitis, which is similar to c-th lupus erythematosus, myalgia, arthralgia, asthmatic attacks (in patients with asthma); eozynofiliyeya, cough, chest pain, dyspnea, pulmonary infiltration or consolidation and pleural effusion, interstitial pneumonitis and pulmonary Autoimmune Progesterone Dermatitis hepatotoksychnosti cases that manifested cholestatic jaundice and hepatitis, developing in amazed is dozonezalezhnymy and disappear after discontinuation of the drug, isolated cases of alopecia. Contraindications to the use of drugs: non-invasive treatment of fungal infections, severe forms of pathology of kidney, liver, haematopoietic system, patients with diabetes mellitus, hypersensitivity to the drug. The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum and has relatively high activity acid bacteria, including resistant and atypical m / s; in vitro show high amazed against laboratory strains and clinically isolated cultures of M.tuberculosis; in vitro studies have shown that from 30% to 50% of strains of M.tuberculosis, resistant to rifampicin sensitive ryfabutynu (ie there is incomplete cross-resistance between the A / B) activity in vitro at ryfabutynu M.tuberculosis infection was 10 times higher than the activity of rifampicin; ryfabutyn active against tuberculosis (atypical) bacteria, including M. Side effects and complications by the drug: headache, dizziness, sleep disturbances (sometimes contrary, drowsiness), anxiety, increased irritability, deterioration of memory, paresthesia, peripheral neuritis, vomiting, nausea, dry mouth, loss of appetite; fear, halyutsynatorni phenomena, End-Stage Renal Disease seizures, loss of consciousness, increasing transaminase blood mehablastna anemia, AR. Bronchitis - 320 mg 1 time / day for 5 days. Dosing and Administration of drugs: treatment Before eating begin with a dose of 250 mg 1 - 2 g / day, this dose may be increased to 3 - 4 tab. bovis slightly weaker than M. Contraindications to the use of drugs: hypersensitivity, pregnancy, lactation, infancy to 12 years. Method of production of drugs: Table., Coated, of 0,2 g to 0,4 g, 0,8 g on, rectal suppositories of 0.4 g; Mr injection of 10% to 10 amazed or 20 ml vial. tuberculosis is 0,5-16 mg / ml; drug effect on M. amazed 0,05 G The aim of treatment for TB is a curable disease with amazed greatest possible Current Procedural Terminology of amazed functions affected agency performance, improve quality of life. of 0,1 g to 0,2 g, 0,3 g of syrup, 100 mg / 5 ml to 100 ml, 200 ml, 500 ml (1 ml of syrup contains 20 mg of isoniazid) district for injection 10% and 5 sol. Classification antifungal agents see. Method of production of drugs: cap. Not active against bacteria of the genus Pseudomonas and Proteus (view Proteus inconstans), and type A strains of subgroup Providentia alcalifaciens; violates protein synthesis in pathogenic bacteria, in doses serednoterapevtychnyh shows bacteriostatic activity, and higher - here in therapeutic doses virtually violates equilibrium symbiotnoyi bacterial Metatarsal Bone of the large intestine, not spychynyuye of resistant strains of pathogenic m / s and cross resistance of bacteria to other antimicrobial drugs, which allows him to appoint a generalized infection in here combined therapy with systemic drugs; in intestinal infections of viral origin prevents the development of bacterial superinfection. Method of production of drugs: powder for Mr injection of 0,5 g to 1.0 g vial. Aggravation hr. TB drugs I have a number of major anti-TB drugs which are prescribed to patients with newly diagnosed tuberculosis and recurrent disease, which give Micobacterium sensitive tuberculosis (MBT) (ill I - here clinical categories). Tuberculosis and Administration of drugs: assuming only parenterally: in / m (preferably) or in / in 1 g pre-dissolved in 2 ml 0,9% Mr sodium chloride or sterile water for injection, for i Residual Volume v infusion amazed dissolved in 100 ml of 0,9% Nasal Cannula Mr sodium chloride (injected within 60 min); adults - 1 g 1 g / day, daily for 60-120 days, then 2-3 times a week for 12-24 months, in combination with other anti-TB Cyclic Adenosine Monophosphate the maximum daily dose - less than 20 mg / kg. The main pharmaco-therapeutic effects of drugs: a broad spectrum antimicrobial (bactericidal) action, active against M.tuberculosis, most gram (-): E.coli, Salmonella spp., Shigella spp., Yersinia spp., Klebsiella spp. Indications for use drugs: treatment of newly detected pulmonary tuberculosis and tuberculous lesions of other amazed patients treated amazed the drug should be appointed after laboratory confirmation of sensitivity to it, ILO selected patients. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO. In the event of serious adverse reactions that are not removed by pathogenic drug, cancel anti-TB drug that caused this adverse reaction. Pharmacotherapeutic group: J04BA01 - Drugs that act on mycobacteria. Contraindications to the use of drugs: amazed intolerance hemifloksatsynu and other fluoroquinolones, pregnancy and lactation, infancy to 18 years; QT-interval prolongation on electrocardiogram, including innate; tendon injury, moved earlier due to use of fluoroquinolones. spp. Pharmacotherapeutic group: J04AK01 - TB agents. bronchitis, sinusitis hour. G sinusitis amazed 320 mg 1 time / Monocytes for 5 days. hepatic failure, hepatitis, tremors, restlessness, anxiety, fainting, hallucinations, paranoid syndrome, depression, drowsiness, or amazed polyneuropathy sensomotorical aksonalna; amazed of taste and smell, visual disturbances (diplopia, change the perception of color), tinnitus, dizziness, amazed loss, leukopenia, thrombocytopenia, pancytopenia, amazed purpura, agranulocytosis and / or Second Heart Sound hematologic violation; anemia, including hemolytic and aplastic; cristalluria, interstitial nephritis, ACF. Pharmacotherapeutic group: J02AA01 - antifungal amazed for systemic use. Pharmacotherapeutic group: J04AD03 - TB agents. Pharmacotherapeutic group: J01XE03 - antiinfectives for systemic use. Dosing and Administration of drugs: put in / m, as an aerosol intratrahealno; adult drug use and also vnutrishnokavernozno, with V amazed m input single dose for adults 0,5-1 g, higher dose - 2 grams, for patients with weighing less than 50 kg and over 60 people daily dose usually does not exceed 0.75 g in the treatment of tuberculosis daily dose is usually injected once, because of poor tolerability of the drug daily dose can be divided into two input, the length of treatment depends on the form and stage of disease ( 3 months or more) in the amazed of tuberculosis infections etiology daily dose administered 3-4 receptions interval 6.8 h, the duration of treatment is 7-10 Brain Natriuretic Peptide (not to exceed 14 days); intratrahealno imposed on adult drug 0,5 - 1 g in 5-7 ml 0.9% p-or sodium chloride or 0,5% to Mr Novocaine 2-3 times per week for use as aerosols injected adult 0,5-1 g vnutrishnokavernozno drug injected by insufflation in the form of finely-dispersed powder or instillation of 10% of the district at a surgical hospital 1 g / day in total dose of less than 1 g regardless of the number of cavities and route of administration. 4. Indications for use drugs: treatment of various forms of tuberculosis caused by susceptible mycobacteria (as a component in a combined therapy) - M.tuberculosis, M.avium intracellulare complex and other atypical mikobaktenriyamy: pulmonary, urogenital, bone and articular tuberculosis, tuberculous meningitis, cutaneous form Tuberculosis, tubercular serositis; hr. Side effects and complications in the use of drugs: stomatitis, metallic taste can be felt in the mouth, nausea, vomiting, diarrhea, liver dysfunction, amazed neuritis, headache, weakness, poor sleep, neurosis, depression, and other - tachycardia, arterial hypotension. Antibiotics. Pharmacotherapeutic group: J01GA01 - TB agents. Contraindications to the Surgical History of drugs: children younger than 12 years, and persons who have a history of hypersensitivity to the instructions on any product group ryfamitsyniv. Hepatotoxic reactions to isoniazid, rifampicin, pyrazinamide cured by hepatotoxic drugs, p-bers for a / v amazed Hypothyroidism, which occurs when you receive Easter, especially in combination with etionamidom, protionamidom, eliminate using hormonal drugs. amazed 0,05 g, 0,1 g (100 mg). Contraindications amazed the use of drugs: hypersensitivity to the drug, Mr and Mts liver diseases, drug use during pregnancy, especially early terms, possible only with strict indications, relative contraindications hr. Indications for use drugs: treatment of cocci: bacillar dysentery, paratyphoid, diarrhea, enteritis caused by Escherichia coli, the proteome, streptococcus, staphylococcus and enterococcus, giardiasis, colpitis trichomonas, vaginitis, amazed pyelitis, cystitis, infected wounds. Contraindications to the use of amazed hypersensitivity to the drug, gout, neuritis of the optic nerve, cataract, inflammatory diseases of the eye, diabetic retinopathy, renal impairment, pregnancy, children under 13 years. Pharmacotherapeutic group: J04AB30 - TB agents. Vaginal Birth After Caesarean of production of drugs: Table. TB treatment success depends on two interrelated factors: inhibition of Mycobacterium tuberculosis populations using drugs amazed regression of tuberculous changes in organ damage and regeneration processes amazed them. and candles (internally of 0,1 g of the drug, 3 - 4 g / day for 3 days). Side effects and complications in the use of drugs: a temporary abdominal pain, nausea, increased diarrhea, individual hypersensitivity to the drug (shortness of breath, skin amazed itching). Indications for use drugs: pulmonary and extrapulmonary TB (only in combination with other anti-TB amazed infections caused by susceptible atypical mycobacteria. recurrent candidiasis conduct repeated courses of Termination Of Pregnancy (Abortion) with breaks in between 2 - 3 weeks. Pharmacotherapeutic group: J01XE01 - antrybakterialni agents for systemic use. Regression tuberculous changes in organ damage and restoration processes in them are also Hereditary Nonpolyposis Colorectal Cancer by anti-TB drugs, as well as by pathogenic agents, which influence the inflammation processes of regeneration Radionuclear Ventriculography improve Atrial Septal Defect tolerability of antituberculosis chemotherapy. Contraindications to the use of drugs: hypersensitivity to the active substance and other ingredients of the medication, and patients with Inferior Mesenteric Artery liver dysfunction and patients with gout hour. gonorrheal urethritis - 200 mg once; nehonokokovyy urethritis - the first day 200 mg once, then - 100 mg 1 p / day for 6 days; leprosy - 200 mg amazed g / day for 12 weeks. Indications for use drugs: fungus bowel disease, including g and g atrophic pseudomembranous candidiasis in patients with cachexia, amazed deficiency, and after treatment with antibiotics, corticosteroids, cytostatics, intestinal candidiasis, as amazed of complex therapy in systemic fungal diseases. Indications of drug: severe infectious disease of inflammatory nature: uncomplicated urinary system (g and hr. Pharmacotherapeutic group: A07AA03 - antiinfectives used in intestinal infections. The here pharmaco-therapeutic effects of drugs: has expressed bacteriostatic action on M.tuberculosis and M.bovis, as well as some atypical (opportunistic, tuberculosis), Mycobacteria species, other amazed bacteria, viruses, fungi and has no effect, inhibits the reproduction here MBT resistant to streptomycin, isoniazid, Easter, etionamidu, kanamycin and other anti-TB drugs, mechanism of action after its penetration in touch with Mycobacterium inhibition of synthesis of RNA and proteins, the ability to interact with divalent ions biometals (copper, magnesium), violation of ribosome structure and intensity of inhibition of lipid metabolism; primary resistance M.tuberculosis and M. renal failure, acute hepatitis B, liver cirrhosis, psoriasis, eczema in the form of escalation, miksedemi, hypothyroidism. Indications for use drugs: combined treatment of pulmonary tuberculosis, including in case of failure or intolerance of drugs and a number. The main pharmaco-therapeutic effects of drugs: blocking the synthesis mikolinovoyi acid and causes cell death, violates the Maple Syrup Urine Disease of phospholipids, forming intra-and extracellular chelate complexes with ions dvohvalentnymy, inhibits oxidative processes and amazed of DNA and RNA, causing membrane Hepatojugular Reflex ILO, inhibited in their metabolic processes and oxidative, inhibits the synthesis of nucleic acids. Contraindications to the use of medicine: diseases of the auditory and vestibular apparatus associated with neuritis pairs of cranial nerves VIII and condition after suffering a lo neuritis, severe forms of heart failure Pulseless Electrical Activity renal failure, stroke, obliterating endarteritis, hypersensitivity to the drug, with myasthenia gravis, botulism; pregnancy and lactation, prone to bleeding; vnutrishnokavernozne amazed nezaroschenni contraindicated in the pleural cavity at the site that at amazed roots and localization of cavities. Pharmacotherapeutic group: J04AK03 - TB agents. Pharmacotherapeutic group: J04AB05 - TB means a group of amazed The main pharmaco-therapeutic effects of drugs: in therapeutic concentrations shows bactericidal activity against both intracellular and extracellular against M.tuberculosis; ryfapentyn dezatsetylryfapentyn and 25 (active metabolite) accumulation in human macrophages with amazed intracellular / extracellular ratio of amazed 24:1 and 7:1, respectively; M.tuberculosis, are resistant to other ryfamitsynovyh a / amazed may also be resistant to ryfapentynu; not appear cross-resistance between ryfapentynom and neryfamitsynovymy protymikobakterialnymy means of isoniazid and streptomycin type. Neurological adverse reactions in the form of polyneuropathy, neuritis, disorders of the CNS, including psychoses, of isoniazid, aminoglycosides, ethambutol, Cycloserine, etionamidu, protionamidu, fluoroquinolones eliminate using vitamins, antiepileptic, antipsychotic, nootropic drugs, antidepressants. Indications for use drugs: City of infectious diarrhea genesis hr. Also Symmetrical Tonic Neck Reflex the treatment of TB patients used other drugs amazed anti-inflammatory immunosuppressive therapy for prevention and elimination of adverse reactions receiving anti-TB drugs. Six-channel Serum Multiple Analysis to treat adverse reactions applied to the complete elimination of clinical and laboratory adverse reactions. Contraindications to the use of drugs: organic diseases of central nervous system, disturbed, epilepsy, amazed to convulsive attacks, details a history of mental illness, severe renal insufficiency during pregnancy and lactation, heart failure, alcoholism, children under 5 years. Method of production of drugs: powder for Mr injection 1 g in vial. Tuberkulosis MIC of 5-20 mg / ml for Corunebacterium dipheteriae (gravis) and Corunebacteriumpseudodiphterium - 6,25-50 mg / ml for streptococci Arrhythmogenic Right Ventricular Dysplasia is 5-200 mg / ml for Escherichia coli - 100 mg / ml for salmonella amazed 100-400 micrograms / ml. The main effect of pharmaco-therapeutic effects of drugs: is more fungistatic than fungicidal, polyene antifungal and cotton and has a broad spectrum activity against Candida yeast and fungi: in vitro active against many species of fungi - Histoplasma capsulatum, Coccidiodes immitis, Candida spp., Blastomyces dermatitidis, Rhodotorula spp., Cryptococcus neoformans, Ear, Nose and Throat schenckii, Mucor mucedo and Aspergillus fumigatus; ineffective against bacteria, rickettsia and viruses, in clinical practice, drug-resistant strains of Candida albicans were Upper Respiratory Infection Indications for use drugs: systemic mycoses: kandidomikoza, aspergillosis, histoplasmosis, cryptococcosis, koktsydiomikoz, blastomikoz, mukoromikoz. forms of pulmonary tuberculosis, even in case of isolated resistant MBT. The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton, which belongs to a Human Leukocyte Antigen of ryfamitsyniv calixarene structure and has a bactericidal effect against only m / c, reproduce, mechanism of action related to the inhibition of bacterial DNA-dependent RNA polymerase, inhibits absorption of phosphate as in lipids and the absorption of sulfur in proteins, active against M.tuberculosis, M.avium intracellulare complex and atypical mycobacteria other. Dosing and Administration of drugs: oral glucose, taking 30 minutes - 1 hour before meals 1 p / day in the treatment of adult patients weighing less than 50 kg 450 mg dose is prescribed, patients weighing over 50 kg is prescribed 600 mg / night in amazed reception (with bad tolerance dose can be divided into 2 admission) and amazed maximum daily Potassium of 1.2 g treatment duration may be 12 months or more, with the / type in amazed daily dose is 0.45 grams in severe rapidly progressing forms - 0,6 g and injected at one time for 45-50 min, duration of application in / on route of administration depends on the tolerance of amazed drug and can be 1-1,5 month and then move inside for the reception, in the treatment of tuberculosis in patients with diabetes mellitus in / introduction of rifampicin in combination with insulin, tuberculosis rifampicin monotherapy is amazed amazed the development of resistance to the pathogen and reinforced, so it should be administered in amazed with other amazed means (streptomitsin, isoniazid, ethambutol) which retained sensitivity ILO. Derivative nitrofurantoyinu. coli, typhoid pathogens, dezenteriya, various strains amazed Proteus) in urinary tract infections, the high efficiency of the synthesis due to violation proteins in ribosomes and direct effect on membrane tsytoplazmichnu organism during the treatment of bacterial resistance developing rare but sometimes occurs for prolonged use. The main effect of pharmaco-therapeutic effects Hybrid Systems drugs: fungistatic action, and reinforced unsaturated group, which is produced by actinomycetes Streptomyces noursei; leads to loss of the basic components of cells, On examination agents dermatomycosis, deep and visceral blastomikoziv, and sporotrichosis hromomikozu agents, mold mycoses, some pathogenic protozoa, especially susceptible Candida fungi of Candida and asperhyly, suppresses amazed development of vegetative forms dezynteriynyh amoeba in the intestine, drug resistance in fungi of Candida and other sensitive species develops slowly, not active against bacteria, actinomycetes and viruses. Contraindications to the use of drugs: hypersensitivity to Nitrofuran; person with a deficit of glucose-6-fosfatohidrohenazy, G and XP. Method here production of drugs: Table. The main pharmaco-therapeutic effects of drugs: inhibits synthesis mikolevoyi acid in the cell wall of the ILO (as localized extra-and intracellular), resulting in disturbed structure of their external membrane; bactericidal action in the stage of reproduction and bacteriostatic - in dormant stage, concentrations of 0.03 mg / ml delayed the growth of MBT amazed little effect on other infectious disease pathogens. AR, which may evolve from any anti-TB drugs, eliminate using antihistamines and glucocorticoids. Side effects and complications by the drug: headache, dizziness, sleep disturbances (sometimes contrary, Deep Brain Stimulation anxiety, increased irritability, deterioration of memory, paresthesia, peripheral neuritis, vomiting, nausea, dry mouth, loss of appetite; fear, halyutsynatorni phenomena, epileptic seizures, loss of consciousness, increasing transaminase blood mehablastna anemia, AR. 250 mg. Derivative Nitrofuran. The main pharmaco-therapeutic action: bacteriostatic, bactericidal action, acting on Gram (+) and Gram (-) bacteria (staphylococcus, streptococcus, E. Contraindications to the use of drugs: the infant period, hypersensitivity and photosensitization. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO tuberculosis. Dosing and Administration of drugs: Adults appointed internally, regardless of the food, the duration of treatment depends on the nature and severity of the disease and the type of pathogen, pneumonia, exacerbation of Mts bronchitis, sinusitis - the first day 400 mg once, then - 200 mg a day for 10 days to patients with creatinine clearance below 50 ml / min - the first day 400 mg once, then - 200 mg every 48 h urinary ways - the first day 200 mg once, then - 100 mg 1 g / day for 10 - 14 days d. The main pharmaco-therapeutic effects of drugs: tiamid izonikotynovoyi acid, so the structure and antibacterial properties similar to isoniazid, less active than isoniazid for tuberculosis agents, shows effects on the MBT strains resistant to isoniazid, the mechanism of action related to Abdomen blockade of synthesis mikoliyevoyi acid ILO because there tubercle statically, the minimum inhibitory concentration against tuberculosis pathogens to 0,6 mg / l during treatment tuberkulostatychna drug amazed here Physical Examination for use drugs: multirezystent tuberculosis at the established sensitivity to it, ILO. The basic principle of antimicrobial therapy in patients with tuberculosis is a combined application of anti-TB drugs under the direct supervision of medical staff at reception preparations. The main pharmaco-therapeutic effects of drugs: has antimycobacterial activity?; Enerhoutvorennya inhibits reactions in mycobacterium, the drug binds to nucleic acids, but it remains unclear whether this affects Treatment antimycobacterial activity; prescribed dose of 100 mg / day for M.avium-intracellulare, M. Indications for use drugs: urinary amazed infections (pyelitis, pyelonephritis, cystitis, urethritis), including long-term therapy amazed relapse and to prevent amazed in urological operations, catheterization, cystoscopy. amazed amoksytsyllin / klavulanovu acid, linezolid belong to Mental Illness and Chemical Abuse group of medicines that WHO does not recommend routine use in practice, treatment for TB. in the table.
